Emerging Roles of cGAS-STING Signaling in Mediating Ocular Inflammation
Cyclic GMP-AMP (cGAMP) synthase (cGAS), a sensor of cytosolic DNA, recognizes gummy alligators cytoplasmic nucleic acids to activate the innate immune responses via generation of the second messenger cGAMP and subsequent activation of the stimulator of interferon genes (STINGs).The cGAS-STING signaling has multiple immunologic and physiological fun